Question Do critically ill adult patients hospitalized for suspected sepsis and treated with intravenous antibiotics based on procalcitonin (PCT) or C-reactive protein (CRP) protocols, have a safe reduction in treatment duration compared with standard care?Findings In this multicenter, randomized trial of 2760 patients, the daily PCT-guided protocol reduced total antibiotic duration and had noninferior all-cause… Continue reading Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected #SepsisThe ADAPT-Sepsis Randomized Clinical Trial
Tag: procalcitonin
Serum #procalcitonin levels associate with #Clostridioides difficile infection in patients with #inflammatory bowel disease
Clostridioides difficile infection (CDI) is a major cause of morbidity among patients with inflammatory bowel disease (IBD). Diagnostic biomarkers for early detection of CDI are needed in clinical practice. The relationship between serum procalcitonin and CDI in IBD patients has not been investigated so far. Therefore, we aimed to evaluate the usefulness of measuring serum… Continue reading Serum #procalcitonin levels associate with #Clostridioides difficile infection in patients with #inflammatory bowel disease
Elevated serum #procalcitonin levels and their association with the prognosis of patients with liver #cirrhosis
Bacterial infection is a major complication in patients with liver cirrhosis. Procalcitonin is an early diagnostic marker of bacterial infection. This study aimed to investigate the association between the serum procalcitonin levels and the prognosis of patients with liver cirrhosis.. The serum procalcitonin level was higher (≥0.05 ng/mL) in 151 (64%) patients, and it was significantly… Continue reading Elevated serum #procalcitonin levels and their association with the prognosis of patients with liver #cirrhosis
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