AbstractObjective To estimate the comparative effectiveness of combination therapy with hydroxychloroquine (HCQ) and azithromycin for coronavirus disease 2019 (COVID-19)- related death based on a large monocentric cohort independent of investigators’ putative biases in a real-world setting.Design Retrospective monocentric cohort study, with comprehensive data collection authenticated by an external bailiff and death reports from a national… Continue reading Early Treatment with Hydroxychloroquine and Azithromycin: A ‘Real-Life’ Monocentric Retrospective Cohort Study of 30,423 COVID-19 Patients
Tag: Hydroxychloroquine
Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized Trial
Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized TrialKarin Ried, Taufiq BinJemain, Avni Sali Published: November 25, 2021 (see history) DOI: 10.7759/cureus.19902 Cite this article as: Ried K, BinJemain T, Sali A (November 25, 2021) Therapies to Prevent Progression of… Continue reading Therapies to Prevent Progression of COVID-19, Including Hydroxychloroquine, Azithromycin, Zinc, and Vitamin D3 With or Without Intravenous Vitamin C: An International, Multicenter, Randomized Trial
#Hydroxychloroquine and Mortality Among Patients With Systemic #Lupus Erythematosus in the General Population
Hydroxychloroquine (HCQ) has been associated with improved survival among patients with systemic lupus erythematosus (SLE) from tertiary referral centers. We aimed to determine the potential impact of HCQ use on the risk of mortality among SLE patients in the general population. MethodsWe conducted a nested case–control study within an incident SLE cohort from the entire… Continue reading #Hydroxychloroquine and Mortality Among Patients With Systemic #Lupus Erythematosus in the General Population
A living WHO guideline on drugs to prevent #covid-19
..The linked systematic review and network meta-analysis (6 trials and 6059 participants) found that hydroxychloroquine had a small or no effect on mortality and admission to hospital (high certainty evidence). There was a small or no effect on laboratory confirmed SARS-CoV-2 infection (moderate certainty evidence) but probably increased adverse events leading to discontinuation (moderate certainty… Continue reading A living WHO guideline on drugs to prevent #covid-19
#Hydroxychloroquine or #chloroquine with or without a macrolide for treatment of #COVID-19: a multinational registry analysis
Hydroxychloroquine or chloroquine, often in combination with a second-generation macrolide, are being widely used for treatment of COVID-19, despite no conclusive evidence of their benefit. Although generally safe when used for approved indications such as autoimmune disease or malaria, the safety and benefit of these treatment regimens are poorly evaluated in COVID-19.. ..96 032 patients (mean… Continue reading #Hydroxychloroquine or #chloroquine with or without a macrolide for treatment of #COVID-19: a multinational registry analysis
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