Background: Older adults account for an increasing proportion of emergency department visits for mild traumatic brain injury (mTBI). Although age is incorporated as a high-risk criterion in major clinical decision rules, the operational impact of risk stratification on computed tomography (CT) utilization in very elderly patients remains uncertain.Methods: We conducted a retrospective cohort study including… Continue reading Limited clinical utility of risk stratification for CT decision-making in patients ≥ 75 years with mild traumatic brain injury
Tag: Brain
Reversible alterations of brain acetate metabolism associated with alcohol consumption
#Alcohol consumption elevates circulating acetate. Prior studies showed that acute alcohol reduces brain glucose uptake and increases #brain acetate oxidation. Previously we showed that heavy drinkers have elevated capacity to oxidize brain acetate. Here we repeat the study, adding individuals with alcohol use disorder (AUD). Four groups were enrolled. The analysis data set included Light… Continue reading Reversible alterations of brain acetate metabolism associated with alcohol consumption
Clinical effect of acupuncture on dysphagia following traumatic brain injury based on fiberoptic endoscopic evaluation of swallowing
Objectives: To investigate the clinical therapeutic effect on #dysphagia following traumatic #brain injury (TBI) treated with acupuncture using fiberoptic endoscopic evaluation of swallowing (FEES).Methods: A total of 68 patients with dysphagia following TBI were enrolled and randomly divided into a control group and an acupuncture group, with 34 patients in each group. In the control… Continue reading Clinical effect of acupuncture on dysphagia following traumatic brain injury based on fiberoptic endoscopic evaluation of swallowing
Real-time change in dynamic cerebral autoregulation after acupuncture at GB34 (Yanglingquan): a self-controlled study
Background: Few interventions have been proven to improve dynamic cerebral autoregulation (dCA). #GB34 is a common acupoint for motor function treatment in the clinic. However, the effects of acupuncture on dCA have never been reported and whether acupuncture at GB34 can improve dCA is unknown.Methods: A self-controlled interventional study was conducted. Each participant randomly received… Continue reading Real-time change in dynamic cerebral autoregulation after acupuncture at GB34 (Yanglingquan): a self-controlled study
Liberal versus restrictive #transfusion strategies in patients with acute #brain injury: a systematic review and meta-analysis of randomized controlled trials
Anemia has been observed in up to 46% of individuals with acute brain injury. Blood transfusions are commonly performed to raise hemoglobin levels, so we aimed to compare the restrictive and liberal blood transfusion strategies in acute brain injury patients.MethodsA systematic search was conducted on Web of Science, Embase, Scopus, Cochrane, and Medline/PubMed up to… Continue reading Liberal versus restrictive #transfusion strategies in patients with acute #brain injury: a systematic review and meta-analysis of randomized controlled trials
The declining #mental #health of the #young and the global disappearance of the #unhappiness hump shape in #age
Across many studies subjective well-being has followed a U-shape in age, declining until people reach middle-age, only to rebound subsequently. Ill-being has followed a mirror-imaged hump-shape. Using graphical and regression analyses of repeat cross-sectional micro-data from the United States and the United Kingdom, we show this empirical regularity has been replaced by a monotonic decrease… Continue reading The declining #mental #health of the #young and the global disappearance of the #unhappiness hump shape in #age
Human #thalamocortical structural connectivity develops in line with a hierarchical axis of #cortical plasticity
Human cortical development follows a hierarchical, sensorimotor-to-association sequence. The brain’s capacity to enact this sequence indicates that it relies on unknown mechanisms to regulate regional differences in the timing of cortical maturation. Given evidence from animal systems that thalamic axons mechanistically regulate periods of cortical plasticity, here we evaluate in humans whether the development of… Continue reading Human #thalamocortical structural connectivity develops in line with a hierarchical axis of #cortical plasticity
DunedinPACNI estimates the longitudinal Pace of #Aging from a single brain #image to track health and disease
To understand how aging affects functional decline and increases disease risk, it is necessary to develop measures of how fast a person is aging. Using data from the Dunedin Study, we introduce an accurate and reliable measure for the rate of longitudinal aging derived from cross-sectional brain magnetic resonance imaging, that is, the Dunedin Pace… Continue reading DunedinPACNI estimates the longitudinal Pace of #Aging from a single brain #image to track health and disease
Active #Travel Mode and Incident #Dementia and #Brain Structure
Importance Active travel modes, such as walking and cycling, are feasible and readily embraced forms of physical activity, but their association with dementia risk and brain structure remains unclear.Objectives To investigate the long-term association between travel modes and dementia risk and brain structural metrics and to evaluate whether genetic predisposition could modify the association between… Continue reading Active #Travel Mode and Incident #Dementia and #Brain Structure
2 Medical News 