#Subretinal Photovoltaic Implant to Restore #Vision in Geographic Atrophy Due to AMD

Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in such persons currently exist. The photovoltaic retina implant microarray (PRIMA) system combines a subretinal photovoltaic implant and glasses that project near-infrared light to the implant in… Continue reading #Subretinal Photovoltaic Implant to Restore #Vision in Geographic Atrophy Due to AMD

#Vision Impairment and the Population Attributable Fraction of #Dementia in Older Adults

Importance  Vision impairment is a potentially modifiable risk factor for dementia. Although few prior studies have estimated the contribution of vision impairments to dementia, none have reported on multiple objectively measured vision impairments (eg, distance and near visual acuity and contrast sensitivity) in a nationally representative sample of older adults.Objective  To quantify population attributable fractions of dementia… Continue reading #Vision Impairment and the Population Attributable Fraction of #Dementia in Older Adults

#Vision Impairment and the Population Attributable Fraction of #Dementia in Older #Adults

Importance  Vision impairment is a potentially modifiable risk factor for dementia. Although few prior studies have estimated the contribution of vision impairments to dementia, none have reported on multiple objectively measured vision impairments (eg, distance and near visual acuity and contrast sensitivity) in a nationally representative sample of older adults.Objective  To quantify population attributable fractions of dementia… Continue reading #Vision Impairment and the Population Attributable Fraction of #Dementia in Older #Adults

Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US

Importance  Estimates of the association between visual impairment (VI) and dementia in the US population are based on self-reported survey data or measures of visual function that are at least 15 years old. Older adults are at high risk of VI and dementia so there is a need for up-to-date national estimates based on objective assessments.Objective  To… Continue reading Objectively Measured Visual Impairment and Dementia Prevalence in Older Adults in the US

Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Mitochondrial decline in ageing robs cells of ATP. However, animal studies show that long wavelength exposure (650–900 nm) over weeks partially restores ATP and improves function. The likely mechanism is via long wavelengths reducing nanoscopic interfacial water viscosity around ATP rota pumps, improving their efficiency. Recently, repeated 670 nm exposures have been used on the… Continue reading Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function

Dual #sensory impairment in older adults and risk of #dementia from the GEM Study

Hearing and vision loss are independently associated with dementia, but the impact of dual sensory impairment (DSI) on dementia risk is not well understood.. ..DSI was significantly associated with higher risk of all‐cause dementia (hazard ratio [HR] = 1.86; 95% confidence interval [CI] = 1.25‐2.76) and Alzheimer's disease (HR = 2.12; 95% CI = 1.34‐3.36).… Continue reading Dual #sensory impairment in older adults and risk of #dementia from the GEM Study