Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial

Limited studies suggest that vitamin D or omega 3 fatty acids (n–3 FAs) supplementation may be beneficial for telomere maintenance; however, evidence from large randomized clinical trials is lacking. We hypothesized that vitamin D or n–3 FAs supplementation reduce leukocyte telomere length (LTL) attrition over time by leveraging the VITamin D and OmegA-3 TriaL (VITAL)… Continue reading Vitamin #D3 and marine ω-3 fatty acids supplementation and leukocyte #telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial

Effect of long-term #caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis

Caloric restriction (CR) modifies lifespan and aging biology in animal models. The Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE™) 2 trial tested translation of these findings to humans. CALERIE™ randomized healthy, nonobese men and premenopausal women (age 21–50y; BMI 22.0–27.9 kg/m2), to 25% CR or ad-libitum (AL) control (2:1) for 2 years. Prior… Continue reading Effect of long-term #caloric restriction on telomere length in healthy adults: CALERIE™ 2 trial analysis

Loving-kindness meditation slows biological aging in novices: Evidence from a 12-week randomized controlled trial

Highlights•Over 12 weeks, loving-kindness meditation buffered telomere attrition. •Telomere length decreased in the mindfulness group and the control group. •The loving-kindness group showed less telomere attrition than the control group. AbstractCombinations of multiple meditation practices have been shown to reduce the attrition of telomeres, the protective caps of chromosomes (Carlson et al., 2015). Here, we… Continue reading Loving-kindness meditation slows biological aging in novices: Evidence from a 12-week randomized controlled trial

Ultra-processed #food consumption and the risk of short telomeres in an elderly population of the Seguimiento Universidad de Navarra (SUN) Project

Telomere length (TL) is a marker of biological age that may be affected by dietary factors through oxidation and inflammation mechanisms. In addition, ultra-processed food (UPF) consumption has increased worldwide and it has been associated with the risk of developing several diseases.. ..This is a cross-sectional study of 886 participants (645 men and 241 women)… Continue reading Ultra-processed #food consumption and the risk of short telomeres in an elderly population of the Seguimiento Universidad de Navarra (SUN) Project