Clinical efficacy and safety of linezolid in intensive care unit patients

AbstractBackgroundTo characterize the population of critically ill patients and infections treated with linezolid in the intensive care unit (ICU), and to evaluate the clinical efficacy and safety of linezolid therapy.MethodsThis multi-center, observational, real-world study was conducted across 52 hospitals between June 9, 2018, and December 28, 2019. Patients who met the following inclusion criteria were… Continue reading Clinical efficacy and safety of linezolid in intensive care unit patients

Effectiveness of #Prone Positioning in Nonintubated Intensive Care Unit Patients With Moderate to Severe Acute Respiratory Distress Syndrome by #Coronavirus Disease 2019

In the treatment for severe acute respiratory distress syndrome (ARDS) from coronavirus disease 2019 (COVID-19), the World Health Organization (WHO) recommends prone positioning (PP) during mechanical ventilation for periods of 12–16 h/d to potentially improve oxygenation and survival. In this prospective observational study, we evaluated the ability of long PP sessions to improve oxygenation in… Continue reading Effectiveness of #Prone Positioning in Nonintubated Intensive Care Unit Patients With Moderate to Severe Acute Respiratory Distress Syndrome by #Coronavirus Disease 2019

Critical Care Utilization for the #COVID-19 Outbreak in Lombardy, Italy Early Experience and Forecast During an Emergency Response

On February 20, 2020, a patient in his 30s admitted to the intensive care unit (ICU) in Codogno Hospital (Lodi, Lombardy, Italy) tested positive for a new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19). He had a history of atypical pneumonia that was not responding to… Continue reading Critical Care Utilization for the #COVID-19 Outbreak in Lombardy, Italy Early Experience and Forecast During an Emergency Response