Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study

BackgroundA subgroup analysis of the COVID-OUT trial's long-term outcome found that starting metformin within 3 days of coronavirus disease 2019 (COVID-19) diagnosis reduced post–COVID-19 condition (PCC) incidence by 63% in overweight or obese individuals. However, its generalizability remains uncertain.ObjectivesTo evaluate the effectiveness of metformin in preventing PCC in adults with overweight or obesity who had… Continue reading Effect of #Metformin on the Risk of Post- #coronavirus Disease 2019 Condition Among Individuals With #Overweight or #Obese: A Population-based Retrospective Cohort Study

A case of biopsy-proven inflammatory dilated #cardiomyopathy following heterologous #mRNA -1273 third-dose immunization

Advances in mRNA vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have helped curb the coronavirus disease 2019 (COVID-19) pandemic and prevent disease onset and severity. Growing cases of vaccine-associated myocarditis (VAM) following SARS-CoV-2 immunization have been reported. Although COVID-19 VAM commonly occurs in young males after the second dose of vaccination, most cases are… Continue reading A case of biopsy-proven inflammatory dilated #cardiomyopathy following heterologous #mRNA -1273 third-dose immunization

A Systematic REVIEW of #Autopsy findings in deaths after #covid-19 vaccination

Highlights•We found that 73.9% of deaths were directly due to or significantly contributed to by COVID-19 vaccination.•Our data suggest a high likelihood of a causal link between COVID-19 vaccination and death.•These findings indicate the urgent need to elucidate the pathophysiologic mechanisms of death with the goal of risk stratification and avoidance of death for the… Continue reading A Systematic REVIEW of #Autopsy findings in deaths after #covid-19 vaccination

Wearing face #masks did not reduce risk of #COVID infection after first Omicron wave, research shows 

After the first Omicron wave, research shows that many of the risks of Covid infection changed Before February 2022, always wearing face masks and being retired were associated with reduced risk, but not after Overseas travel was not associated with increased risk prior to February 2022, but then became a significant risk Peer reviewed – meta-regression- humans  New… Continue reading Wearing face #masks did not reduce risk of #COVID infection after first Omicron wave, research shows 

Inability to work following #COVID-19 vaccination-a relevant aspect for future booster vaccinations

Objectives: COVID-19 vaccination is a key prevention strategy to reduce the spread and severity of SARS-CoV-2 infections. However, vaccine-related inability to work among healthcare workers (HCWs) could overstrain healthcare systems.Study design: The study presented was conducted as part of the prospective CoVacSer cohort study.Methods: This study examined sick leave and intake of pro re nata medication after the… Continue reading Inability to work following #COVID-19 vaccination-a relevant aspect for future booster vaccinations

#Covid symptoms follow a very distinctive #pattern now – as common signs change, doctors discover

IN a short space of just a few years, the symptoms of Covid have changed in some surprising ways. Doctors are finding signs of the diseases are now following a very distinctive pattern. How Covid symptoms are changing thanks to heard immunity from prior infections and vaccines The illness’ past telltale signs, like the loss… Continue reading #Covid symptoms follow a very distinctive #pattern now – as common signs change, doctors discover

Early Treatment with Hydroxychloroquine and Azithromycin: A ‘Real-Life’ Monocentric Retrospective Cohort Study of 30,423 COVID-19 Patients

AbstractObjective To estimate the comparative effectiveness of combination therapy with hydroxychloroquine (HCQ) and azithromycin for coronavirus disease 2019 (COVID-19)- related death based on a large monocentric cohort independent of investigators’ putative biases in a real-world setting.Design Retrospective monocentric cohort study, with comprehensive data collection authenticated by an external bailiff and death reports from a national… Continue reading Early Treatment with Hydroxychloroquine and Azithromycin: A ‘Real-Life’ Monocentric Retrospective Cohort Study of 30,423 COVID-19 Patients

Safety of COVID-19 Vaccines in Patients with Autoimmune Diseases, in Patients with Cardiac Issues, and in the Healthy Population

The coronavirus disease 2019 (COVID-19) has been a challenge for the whole world since the beginning of 2020, and COVID-19 vaccines were considered crucial for disease eradication. Instead of producing classic vaccines, some companies pointed to develop products that mainly function by inducing, into the host, the production of the antigenic protein of SARS-CoV-2 called… Continue reading Safety of COVID-19 Vaccines in Patients with Autoimmune Diseases, in Patients with Cardiac Issues, and in the Healthy Population

Physical interventions to interrupt or reduce the spread of respiratory viruses

...We included 11 new RCTs and cluster‐RCTs (610,872 participants) in this update, bringing the total number of RCTs to 78. Six of the new trials were conducted during the COVID‐19 pandemic; two from Mexico, and one each from Denmark, Bangladesh, England, and Norway. We identified four ongoing studies, of which one is completed, but unreported, evaluating masks… Continue reading Physical interventions to interrupt or reduce the spread of respiratory viruses