Complex diseases, such as coronary artery disease (CAD), are often multifactorial, caused by multiple underlying pathological mechanisms. Here, to study the multifactorial nature of CAD, we performed comprehensive clinical and multi-omic profiling, including serum metabolomics and gut microbiome data, for 199 patients with acute coronary syndrome (ACS) recruited from two major Israeli hospitals, and validated… Continue reading Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease
Tag: CAD
#Coronary artery disease prediction in women and men using chest pain characteristics and risk factors: an observational study in outpatient clinics
..Twenty-four women (5%) and 75 men (15%) were diagnosed with coronary artery disease by invasive coronary angiography or CT angiography during regular care follow-up. Elastic net regression was performed to assess which chest pain characteristics and risk factors were of diagnostic value. The overall model selected age, provocation by temperature or stress, relief at rest… Continue reading #Coronary artery disease prediction in women and men using chest pain characteristics and risk factors: an observational study in outpatient clinics
#Glycated hemoglobin predicts #coronary artery disease in non-diabetic adults
..All patients underwent coronary computed tomography angiography (CCTA) for evaluation of chest pain. The extent of coronary artery stenosis (CAS) was quantified as percentage for each patient based on plaques detected in CCTA. ..Mean blood pressure of the patients was (91.2 ± 11.9 mmHg), BMI (28.3 ± 5.8 kg/m2), serum cholesterol level (174 ± 33.1 mg/dl), and HbA1c levels (mean 5.7 ± 0.45, median 5.7 and… Continue reading #Glycated hemoglobin predicts #coronary artery disease in non-diabetic adults
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