Dupilumab in Patients With Chronic Spontaneous Urticaria: Phase 3 LIBERTY-CSU CUPID Randomized Clinical Trials

Importance: Chronic spontaneous #urticaria (CSU) is an inflammatory disease characterized by recurrent pruritic hives and/or #angioedema. Many patients with CSU remain symptomatic despite standard-of-care, histamine 1-receptor antagonist (H1-AH) treatment. Dupilumab blocks IL-4/IL-13 signaling and is approved in multiple disease states associated with type 2 inflammation. In the phase 3 LIBERTY-CSU CUPID-A trial, dupilumab significantly reduced… Continue reading Dupilumab in Patients With Chronic Spontaneous Urticaria: Phase 3 LIBERTY-CSU CUPID Randomized Clinical Trials

#Urticaria and the risk of #cancer: a Danish population-based cohort study

BackgroundUrticaria has been tentatively linked to cancer, but epidemiological evidence supporting this link is sparse and conflicting. We therefore conducted a population-based cohort study using healthcare databases of the Danish population (January 1980–December 2022). We followed 87,507 people for a median of 10.1 years after first hospital contact for urticaria.ObjectivesTo examine associations of a hospital… Continue reading #Urticaria and the risk of #cancer: a Danish population-based cohort study