The Omicron variant of SARS-CoV-2 has been reported to cause milder disease in adults but lead to increased hospital admissions in children. How can we compare disease severity in Omicron and Delta infections, and how should differences be interpreted? Measuring COVID-19 disease severity in a population has been important for understanding the public health impact… Continue reading Estimating disease severity of Omicron and Delta SARS-CoV-2 infections
Tag: delta
Early insight into #antibody-dependent enhancement after SARS-CoV-2 mRNA #vaccination
Current vaccines, which induce a B-cell-mediated antibody response against the spike protein of SARS-CoV-2, have markedly reduced infection rates. However, the emergence of new variants as a result of SARS-CoV-2 evolution requires the development of novel vaccines that are T-cell-based and that target mutant-specific spike proteins along with ORF1ab or nucleocapsid protein. This approach is… Continue reading Early insight into #antibody-dependent enhancement after SARS-CoV-2 mRNA #vaccination
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