Bifidobacterium bifidum MIMBb75 is one of a few probiotic strains that have been shown to be effective in the treatment of irritable bowel syndrome (IBS) and its symptoms. Non-viable strains might have advantages over viable bacteria for product stability and standardisation, as well as for tolerability because safety concerns have been raised for specific patient… Continue reading Heat-inactivated #Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of #irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial
Tag: bifidobacterium
Intratumoral accumulation of gut #microbiota facilitates CD47-based immunotherapy via STING signaling
..Using one defined anaerobic gut microbiota to track whether microbiota interact with host immunity, we observed that Bifidobacterium facilitates local anti-CD47 immunotherapy on tumor tissues through the capacity to accumulate within the tumor microenvironment. Systemic administration of Bifidobacterium leads to its accumulation within the tumor and converts the nonresponder mice into responders to anti-CD47 immunotherapy… Continue reading Intratumoral accumulation of gut #microbiota facilitates CD47-based immunotherapy via STING signaling
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