Tag: pregnacy

RANK links #thymic regulatory T cells to fetal loss and gestational #diabetes in pregnancy

aledopress

Successful pregnancies rely on adaptations within the mother1, including marked changes within the immune system2. It has long been known that the thymus, the central lymphoid organ, changes markedly during pregnancy3. However, the molecular basis and importance of this process remain largely obscure. Here we show that the osteoclast differentiation receptor RANK4,5 couples female sex… Continue reading RANK links #thymic regulatory T cells to fetal loss and gestational #diabetes in pregnancy

Antidepressant use during pregnancy and the risk of gestational diabetes mellitus: a nested case–control study

aledopress

When adjusting for potential confounders, AD use was associated with an increased risk of GDM (aOR 1.19, 95% CI 1.08 to 1.30); venlafaxine (aOR 1.27, 95% CI 1.09 to 1.49) and amitriptyline (aOR 1.52, 95% CI 1.25 to 1.84) were also associated with an increased risk of GDM. Moreover, the risk of GDM was increased with longer duration… Continue reading Antidepressant use during pregnancy and the risk of gestational diabetes mellitus: a nested case–control study