An increased risk of acute bacterial enteric infections has been reported among patients receiving proton pump inhibitor (#PPI) therapy. The risk of acute gastroenteritis (AGE) of viral origin associated with continuous PPI exposure has been less studied ..At least 1 AGE epidemic episode was identified in 3131 patients (1.3%) receiving PPI therapy and in 4327… Continue reading Association Between Acute #Gastroenteritis and Continuous Use of Proton Pump Inhibitors During Winter Periods of Highest Circulation of Enteric Viruses
Tag: PPI
Randomized Trial of Medical versus Surgical Treatment for Refractory #Heartburn
..Heartburn that persists despite proton-pump inhibitor ( #PPI ) treatment is a frequent clinical problem with multiple potential causes. Treatments for PPI-refractory heartburn are of unproven efficacy and focus on controlling gastroesophageal reflux with reflux-reducing medication (e.g., baclofen) or antireflux surgery or on dampening visceral hypersensitivity with neuromodulators (e.g., desipramine). Prerandomization procedures excluded 288 patients:… Continue reading Randomized Trial of Medical versus Surgical Treatment for Refractory #Heartburn