Malaria, a preventable parasitic disease, causes most child deaths in sub-Saharan Africa (SSA). Reliable cause-of-death data are essential to evaluate progress toward the national and global malaria control goals. However, civil registration and vital statistics are often weak and incomplete in many low- and middle-income countries. In such circumstances, verbal autopsy (VA) provides an alternative… Continue reading Comparison of verbal autopsy using a large #language model to biologically confirmed causes of death for #malaria and other communicable diseases among children in six sub-Saharan African countries
Tag: Malaria
Functional human #IgA targets a conserved site on #malaria sporozoites
A role for IgA in malariaImmunoglobulin (Ig)A is known to play a protective role against pathogens at mucosal surfaces. However, the protective effects of IgA in the serum are less well understood, particularly in the context of pathogens such as Plasmodium falciparum. To address this question, Tan et al. isolated and characterized serum IgA from… Continue reading Functional human #IgA targets a conserved site on #malaria sporozoites
FDA Approves Only Drug in U.S. to Treat Severe #Malaria
Today, the U.S. Food and Drug Administration approved artesunate for injection to treat severe malaria in adult and pediatric patients. Treatment of severe malaria with intravenous (IV) artesunate should always be followed by a complete treatment course of an appropriate oral antimalarial regimen. Prior to this approval, IV artesunate was only available to patients through… Continue reading FDA Approves Only Drug in U.S. to Treat Severe #Malaria
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