Atypical #gut microbial ecosystem from athletes with very high exercise capacity improves insulin sensitivity and muscle glycogen store in mice

Gut bacterial ecosystem is linked to host’s exercise capacity independent of food habits• Despite reduced bacterial diversity, endurance athletes exhibit higher fecal SCFA levels• Gut microbiota from athletes improves insulin sensitivity of transplanted mice• The gut bacterial ecosystem might be driven by access to energy resources left by the hostSummaryAlthough the gut microbiota is known… Continue reading Atypical #gut microbial ecosystem from athletes with very high exercise capacity improves insulin sensitivity and muscle glycogen store in mice

Safety and efficacy of faecal #microbiota transplantation in patients with mild to moderate #Parkinson’s disease (GUT-PARFECT): a double-blind, placebo-controlled, randomised, phase 2 trial

Dysregulation of the gut microbiome has been implicated in Parkinson's disease (PD). This study aimed to evaluate the clinical effects and safety of a single faecal microbiota transplantation (FMT) in patients with early-stage PD.MethodsThe GUT-PARFECT trial, a single-centre randomised, double-blind, placebo-controlled trial was conducted at Ghent University Hospital between December 01, 2020 and December 12,… Continue reading Safety and efficacy of faecal #microbiota transplantation in patients with mild to moderate #Parkinson’s disease (GUT-PARFECT): a double-blind, placebo-controlled, randomised, phase 2 trial