#Atopic eczema and #fracture risk in adults: A population-based cohort study

..Those with eczema had increased risk of hip (HR, 1.10; 99% CI, 1.06-1.14), pelvic (HR, 1.10; 99% CI, 1.02-1.19), spinal (HR, 1.18; 99% CI, 1.10-1.27), and wrist (HR, 1.07; 99% CI, 1.03,-1.11) fractures. We found no evidence of increased proximal humeral (HR, 1.06; 99% CI, 0.97-1.15) fracture risk. Fracture risk increased with increasing eczema severity,… Continue reading #Atopic eczema and #fracture risk in adults: A population-based cohort study

Phase 2a randomized, placebo-controlled study of anti–IL-33 in peanut #allergy

IL-33, found in high levels in participants with allergic disorders, is thought to mediate allergic reactions. Etokimab, an anti–IL-33 biologic, has previously demonstrated a good safety profile and favorable pharmacodynamic properties in many clinical studies ..Efficacy measurements for active vs. placebo participants at the day 15 and 45 food challenge (tolerating a cumulative 275 mg… Continue reading Phase 2a randomized, placebo-controlled study of anti–IL-33 in peanut #allergy