Tag: zolpidem

Comparison of #Lemborexant With Placebo and #Zolpidem Tartrate Extended Release for the Treatment of Older Adults With #Insomnia Disorder

aledopress

..Both doses of lemborexant therapy demonstrated statistically significant greater changes from baseline on objective sleep onset as assessed by latency to persistent sleep (log transformed) that was measured using polysomnography at the end of 1 month of treatment (nights 29 and 30) compared with placebo.. For nights 29 and 30, as measured using polysomnography, the… Continue reading Comparison of #Lemborexant With Placebo and #Zolpidem Tartrate Extended Release for the Treatment of Older Adults With #Insomnia Disorder

Reducing #Suicidal Ideation Through #Insomnia Treatment (REST-IT): A Randomized Clinical Trial

aledopress

..Zolpidem-CR had a robust anti-insomnia effect, especially in patients with the most severe insomnia symptoms. No significant treatment effect was observed on the Scale for Suicide Ideation (least squares mean estimate=−0.56, SE=0.83, 95% CI=−2.19, 1.08), but the reduction in scores was significantly positively related to improvement in insomnia after accounting for the effect of other… Continue reading Reducing #Suicidal Ideation Through #Insomnia Treatment (REST-IT): A Randomized Clinical Trial