Laughing gas improves depressionAbout one-third of individuals suffering from depression are at risk for treatment resistance. Whereas inhaled 50% nitrous oxide has early antidepressant effects on individuals with treatment-resistant major depression (TRMD), adverse effects can occur at this concentration. In this phase 2 clinical trial, Nagele et al. studied the effects of a single 1-hour… Continue reading A phase 2 trial of inhaled #nitrous oxide for treatment-resistant major #depression