Background: Despite the key pathogenetic role of the complement cascade in various immune-mediated kidney diseases, the clinical significance of serum C3/C4 levels in conditions where most patients exhibit complement levels within normal limits, such as membranous nephropathy (MN) and ANCA (antineutrophil cytoplasmic antibody)-glomerulonephritis (ANCA-GN), remains underexplored. This study focused on the clinico-pathological correlates of serum… Continue reading Lower serum C3 levels are associated with glomerulosclerosis in membranous nephropathy and ANCA-glomerulonephritis
Tag: glomerulonephritis
Clinicopathologic characteristics and long-term outcomes in glomerulonephritis with crescent formation: a 20-year single-center cohort study
IntroductionCrescentic #glomerulonephritis (GN) is among the most aggressive glomerular diseases, defined by extensive crescent formation and rapid loss of kidney function.ObjectiveTo evaluate clinical, laboratory, and histopathologic determinants of end-stage kidney disease (ESKD) and overall survival (OS), and to identify associated factors of poor outcomes in patients with crescentic GN (cGN) and GN with crescent formation.MethodsThis… Continue reading Clinicopathologic characteristics and long-term outcomes in glomerulonephritis with crescent formation: a 20-year single-center cohort study
