Glioblastoma (GBM) is one of the most difficult cancers to effectively treat, in part because of the lack of precision therapies and limited therapeutic access to intracranial tumor sites due to the presence of the blood-brain and blood-tumor barriers. We have developed a precision medicine approach for GBM treatment that involves the use of brain-penetrant… Continue reading A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent #glioblastoma
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