Key PointsQuestion Do patients with large joint replacements have elevated levels of arthroplasty-relevant metals in blood and cerebrospinal fluid (CSF)?Findings This cross-sectional study with 204 patients found blood levels of cobalt, chromium, titanium, niobium, and zirconium to be significantly higher in patients with large joint replacements compared with arthroplasty-naive control participants. Cobalt levels in CSF… Continue reading #Metal Concentrations in #Blood and #Cerebrospinal Fluid of Patients With #Arthroplasty Implants
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