Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and difficult to predict. This is a major challenge for effective clinical management.Objective We aimed to provide accurate AN risk stratification in UC patients with LGD. We hypothesised that… Continue reading Low-coverage whole genome sequencing of low-grade #dysplasia strongly predicts advanced neoplasia risk in ulcerative #colitis