Aspirin use for cancer prevention: A systematic review of public, patient and healthcare provider attitudes and adherence behaviours

Highlights•Most eligible people offered participation in an aspirin trial accepted. •Among participants, most reported high (≥80%) adherence on a day-to-day basis. •No studies examined uptake and adherence in routine care. •Further research is needed to identify the barriers to using aspirin in practice. AbstractWe undertook a systematic review to synthesise the data on attitudes and …

Continue reading Aspirin use for cancer prevention: A systematic review of public, patient and healthcare provider attitudes and adherence behaviours

Cytokine signature for predicting new-onset prediabetes after acute pancreatitis: A prospective longitudinal cohort study

Highlights•Interleukin-1β at baseline predicts new-onset prediabetes after acute pancreatitis. •Interferon γ at baseline predicts new-onset prediabetes after pancreatitis. •Changes in adaptive immunity may underlie glucose derangements after pancreatitis. AbstractBackground/purposeAcute inflammation of the pancreas often leads to metabolic sequelae, the most common of which is new-onset prediabetes (and, ultimately, diabetes). However, there is a lack of …

Continue reading Cytokine signature for predicting new-onset prediabetes after acute pancreatitis: A prospective longitudinal cohort study