Relationship Between #Ultraprocessed Food Intake and #Cardiovascular Health Among U.S. Adolescents: Results From the National Health and Nutrition Examination Survey 2007–2018

Studies of the association between ultraprocessed foods (UPF) and cardiovascular disease risk factors have been mainly focused on the adult population. This study examined the association between usual percentage of calories (%kcal) from UPF and the American Heart Association's seven cardiovascular health (CVH) metrics among U.S. adolescents aged 12–19 years. MethodsWe used data from the …

Continue reading Relationship Between #Ultraprocessed Food Intake and #Cardiovascular Health Among U.S. Adolescents: Results From the National Health and Nutrition Examination Survey 2007–2018

Role of Adipocyte Na,K-ATPase Oxidant Amplification Loop in #Cognitive Decline and #Neurodegeneration

•Adipocytes induce phenotypical changes in neurodegeneration through adipocyte NKAL.•Adipocyte specific NaKtide inhibited NKAL and improved systemic homeostasis.•NaKtide improved adipocyte phenotype and improved markers of neurodegeneration.•NaKtide improved genomic profile of hippocampus and adipose tissue in WD fed mice. SummaryRecent studies suggest that a western diet may contribute to clinical neurodegeneration and dementia. Adipocyte-specific expression of the …

Continue reading Role of Adipocyte Na,K-ATPase Oxidant Amplification Loop in #Cognitive Decline and #Neurodegeneration

Digging for data: How #sleep is losing out to roster design, sleep disorders, and lifestyle factors

Highlights•Shift start times <06:00, may result in sleep loss resulting in poor alertness. •Risk of sleep disorders increased with body mass and age. •Prevalence of shiftwork disorder and obstructive sleep apnea in mining is high. •Biomathematical modeling may be used to eliminate or reduce organizational risk. AbstractShift workers employed at a remote mining operation may …

Continue reading Digging for data: How #sleep is losing out to roster design, sleep disorders, and lifestyle factors

Early insight into #antibody-dependent enhancement after SARS-CoV-2 mRNA #vaccination

Current vaccines, which induce a B-cell-mediated antibody response against the spike protein of SARS-CoV-2, have markedly reduced infection rates. However, the emergence of new variants as a result of SARS-CoV-2 evolution requires the development of novel vaccines that are T-cell-based and that target mutant-specific spike proteins along with ORF1ab or nucleocapsid protein. This approach is …

Continue reading Early insight into #antibody-dependent enhancement after SARS-CoV-2 mRNA #vaccination