Synthesis of human #amyloid restricted to #liver results in an #Alzheimer disease–like neurodegenerative phenotype

Several lines of study suggest that peripheral metabolism of amyloid beta (Aß) is associated with risk for Alzheimer disease (AD). In blood, greater than 90% of Aß is complexed as an apolipoprotein, raising the possibility of a lipoprotein-mediated axis for AD risk. In this study, we report that genetic modification of C57BL/6J mice engineered to …

Continue reading Synthesis of human #amyloid restricted to #liver results in an #Alzheimer disease–like neurodegenerative phenotype

Cross-sectional associations of schoolchildren’s #fruit and #vegetable consumption, and meal choices, with their mental well-being: a cross-sectional study

Poor mental well-being is a major issue for young people and is likely to have long-term negative consequences. The contribution of nutrition is underexplored. We, therefore, investigated the association between dietary choices and mental well-being among schoolchildren. Methods Data from 7570 secondary school and 1253 primary school children in the Norfolk Children and Young People …

Continue reading Cross-sectional associations of schoolchildren’s #fruit and #vegetable consumption, and meal choices, with their mental well-being: a cross-sectional study