Day: Aug 6, 2021

Effect of 7 vs 14 Days of #Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With #Urinary Tract InfectionA Randomized Clinical Trial

On By aledopressIn Urology

Determination of optimal treatment durations for common infectious diseases is an important strategy to preserve antibiotic effectiveness. Objective To determine whether 7 days of treatment is noninferior to 14 days when using ciprofloxacin or trimethoprim/sulfamethoxazole to treat urinary tract infection (UTI) in afebrile men. Design, Setting, and Participants Randomized, double-blind, placebo-controlled noninferiority trial of afebrile …

Continue reading Effect of 7 vs 14 Days of #Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With #Urinary Tract InfectionA Randomized Clinical Trial

Extrapolating Long-term Event-Free and Overall Survival With #Dapagliflozin in Patients With #Heart Failure and Reduced #Ejection Fraction

On By aledopressIn Cardiology, Endocrinology

Sodium glucose cotransporter 2 inhibitors reduce morbidity and mortality in patients with heart failure and reduced ejection fraction (HFrEF). Clinicians may find estimates of the projected long-term benefits of sodium glucose cotransporter 2 inhibitors a helpful addition to clinical trial results when communicating the benefits of this class of drug to patients. Objective To estimate …

Continue reading Extrapolating Long-term Event-Free and Overall Survival With #Dapagliflozin in Patients With #Heart Failure and Reduced #Ejection Fraction