lab alert: Changes to CDC RT-PCR for SARS-CoV-2 Testing

Audience: Individuals Performing COVID-19 Testing Level: Laboratory Alert After December 31, 2021, CDC will withdraw the request to the U.S. Food and Drug Administration (FDA) for Emergency Use Authorization (EUA) of the CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel, the assay first introduced in February 2020 for detection of SARS-CoV-2 only. CDC is providing …

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#Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of #SARS-CoV-2

There is an urgent need for antiviral agents that treat SARS-CoV-2 infection. We screened a library of 1,900 clinically safe drugs against OC43, a human beta-coronavirus that causes the common cold and evaluated the top hits against SARS-CoV-2. Twenty drugs significantly inhibited replication of both viruses in vitro. Eight of these drugs inhibited the activity …

Continue reading #Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of #SARS-CoV-2