Association of Oral #Anticoagulation With #Stroke in Atrial #Fibrillation or Heart #Failure: A Comparative Meta-Analysis

Atrial fibrillation and heart failure with reduced ejection fraction (HFrEF) are common sources of cardioembolism. While oral anticoagulation is strongly recommended for atrial fibrillation, there are marked variations in guideline recommendations for HFrEF due to uncertainty about net clinical benefit. This systematic review and meta-analysis evaluates the comparative association of oral anticoagulation with stroke and …

Continue reading Association of Oral #Anticoagulation With #Stroke in Atrial #Fibrillation or Heart #Failure: A Comparative Meta-Analysis

The #CHA2DS2-VASc Score for Risk Stratification of #Stroke in Heart Failure With-vs-Without Atrial #Fibrillation

A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association …

Continue reading The #CHA2DS2-VASc Score for Risk Stratification of #Stroke in Heart Failure With-vs-Without Atrial #Fibrillation