Day: Jul 4, 2021

Infectivology

Review of the Emerging Evidence Demonstrating the Efficacy of #Ivermectin in the Prophylaxis and Treatment of #COVID-19

This is a provisional file, not the final typeset article Article.pdfDownload

Gastroenterology, Neurology

#Gut microbes impact #stroke severity via the trimethylamine N-oxide pathway

Clinical studies have demonstrated associations between circulating levels of the gut-microbiota-derived metabolite trimethylamine-N-oxide (TMAO) and stroke incident risk. However, a causal role of gut microbes in stroke has not yet been demonstrated. Herein we show that gut microbes, through dietary choline and TMAO generation, directly impact cerebral infarct size and adverse outcomes following stroke. Fecal … Continue reading #Gut microbes impact #stroke severity via the trimethylamine N-oxide pathway