#Renal hemodynamics across the adult lifespan: Relevance of #flow pulsatility to chronic kidney disease

Elevated renal flow pulsatility may contribute to the pathogenesis of chronic kidney disease (CKD). The purpose of this study was to investigate the associations among age, renal flow pulsatility, and CKD biomarkers in non-CKD adults and CKD patients. MethodsNon-CKD adults (n = 415) and CKD patients (n = 136) aged between 22 and 83 years underwent the renal blood flow …

Continue reading #Renal hemodynamics across the adult lifespan: Relevance of #flow pulsatility to chronic kidney disease

Adaptive circuit dynamics across human #cortex during evidence accumulation in changing #environments

Many decisions under uncertainty entail the temporal accumulation of evidence that informs about the state of the environment. When environments are subject to hidden changes in their state, maximizing accuracy and reward requires non-linear accumulation of evidence. How this adaptive, non-linear computation is realized in the brain is unknown. We analyzed human behavior and cortical …

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