Timing of #chocolate intake affects hunger, substrate oxidation, and #microbiota: A randomized controlled trial

Eating chocolate in the morning or in the evening/at night, may differentially affect energy balance and impact body weight due to changes in energy intake, substrate oxidation, microbiota (composition/function), and circadian-related variables. In a randomized controlled trial, postmenopausal females (n = 19) had 100 g of chocolate in the morning (MC), in the evening/at night …

Continue reading Timing of #chocolate intake affects hunger, substrate oxidation, and #microbiota: A randomized controlled trial

#Ivermectin for Prevention and Treatment of #COVID-19 InfectionA Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials. Areas of uncertainty:We assessed the efficacy of ivermectin treatment in reducing mortality, in secondary outcomes, and in chemoprophylaxis, among people with, or at high risk of, COVID-19 infection. Data …

Continue reading #Ivermectin for Prevention and Treatment of #COVID-19 InfectionA Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines