Development and prognostic relevance of a histologic grading and staging system for #alcohol-related #liver disease

The SALVE Histopathology Group (SHG) developed and validated a grading and staging system for the clinical and full histological spectrum of alcohol-related liver disease (ALD) and evaluated its prognostic utility in a multinational cohort of 445 patients. MethodsSALVE grade was described by semiquantitative scores for steatosis, activity (hepatocellular injury and lobular neutrophils) and cholestasis. The …

Continue reading Development and prognostic relevance of a histologic grading and staging system for #alcohol-related #liver disease

First case of postmortem study in a patient vaccinated against #SARS-CoV-2

Highlights•We report on a patient with a single dose of vaccine against SARS-CoV-2. •He developed relevant serum titer levels but died 4 weeks later. •By postmortem molecular mapping, we found viral RNA in nearly all organs examined. •However, we did not observe any characteristic morphological features of COVID-19. •Immunogenicity might be elicited, while sterile immunity …

Continue reading First case of postmortem study in a patient vaccinated against #SARS-CoV-2