Association Between Mortality and Levels of Autonomous #Cortisol Secretion by Adrenal #Incidentalomas

Autonomous cortisol secretion in patients with adrenal incidentalomas is associated with increased mortality, but detailed information about the risk associated with specific levels of autonomous cortisol secretion is not available. Objective:To measure the association between mortality and levels of autonomous cortisol secretion in patients with adrenal incidentalomas. Design:Retrospective cohort study. (ClinicalTrials.gov: NCT03919734) Setting:Two hospitals in …

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The Effects of Chronic Exposure to Ambient #Traffic-Related Air #Pollution on #Alzheimerโ€™s Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats

Epidemiological data link traffic-related air pollution (TRAP) to increased risk of Alzheimerโ€™s disease (AD). Preclinical data corroborating this association are largely from studies of male animals exposed acutely or subchronically to high levels of isolated fractions of TRAP. What remains unclear is whether chronic exposure to ambient TRAP modifies AD risk and the influence of …

Continue reading The Effects of Chronic Exposure to Ambient #Traffic-Related Air #Pollution on #Alzheimerโ€™s Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats