#Sarcopenia is independently associated with #parietal atrophy in older adults

On May 12, 2021 By aledopressIn Neurology

Highlights•Sarcopenia was common in old adults living in a retirement community (46.1%). •Sarcopenia had moderate-severe global cortical, parietal and medial temporal atrophy. •Sarcopenia is significantly associated with parietal atrophy in older adults. •Age had a significant relationship with global cortical and medial temporal atrophy. AbstractIntroductionAs populations age, sarcopenia becomes a major health problem among adults …

Continue reading #Sarcopenia is independently associated with #parietal atrophy in older adults

Colonization of the #Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate

On May 12, 2021 By aledopressIn Gastroenterology, Neurology

Protein conformational diseases are characterized by misfolding and toxic aggregation of metastable proteins, often culminating in neurodegeneration. Enteric bacteria influence the pathogenesis of neurodegenerative diseases; however, the complexity of the human microbiome hinders our understanding of how individual microbes influence these diseases. Disruption of host protein homeostasis, or proteostasis, affects the onset and progression of …

Continue reading Colonization of the #Caenorhabditis elegans gut with human enteric bacterial pathogens leads to proteostasis disruption that is rescued by butyrate