Association of Type 2 #Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic #Stroke

Type 2 diabetes mellitus (T2DM) has shown to be associated with carotid plaque vulnerability. However, the impact of T2DM on intracranial artery atherosclerosis is not well‐understood. Purpose To evaluate the association of diabetes and glycemic control with intracranial atherosclerotic plaque characteristics identified by three‐dimensional contrast enhanced MR vessel wall imaging in patients after acute ischemic stroke. Study Type Prospective. Population Two hundred and eighty‐eight symptomatic … Continue reading Association of Type 2 #Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic #Stroke

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Investigating Molecular Mechanisms of Immunotoxicity and the Utility of #ToxCast for Immunotoxicity Screening of Chemicals Added to #Food

The development of high-throughput screening methodologies may decrease the need for laboratory animals for toxicity testing. Here, we investigate the potential of assessing immunotoxicity with high-throughput screening data from the U.S. Environmental Protection Agency ToxCast program. As case studies, we analyzed the most common chemicals added to food as well as per- and polyfluoroalkyl substances (PFAS) shown to migrate to food from packaging materials or … Continue reading Investigating Molecular Mechanisms of Immunotoxicity and the Utility of #ToxCast for Immunotoxicity Screening of Chemicals Added to #Food

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