Association of Type 2 #Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic #Stroke

Type 2 diabetes mellitus (T2DM) has shown to be associated with carotid plaque vulnerability. However, the impact of T2DM on intracranial artery atherosclerosis is not wellโ€understood. Purpose To evaluate the association of diabetes and glycemic control with intracranial atherosclerotic plaque characteristics identified by threeโ€dimensional contrast enhanced MR vessel wall imaging in patients after acute ischemic …

Continue reading Association of Type 2 #Diabetes Mellitus and Glycemic Control With Intracranial Plaque Characteristics in Patients With Acute Ischemic #Stroke

Investigating Molecular Mechanisms of Immunotoxicity and the Utility of #ToxCast for Immunotoxicity Screening of Chemicals Added to #Food

The development of high-throughput screening methodologies may decrease the need for laboratory animals for toxicity testing. Here, we investigate the potential of assessing immunotoxicity with high-throughput screening data from the U.S. Environmental Protection Agency ToxCast program. As case studies, we analyzed the most common chemicals added to food as well as per- and polyfluoroalkyl substances …

Continue reading Investigating Molecular Mechanisms of Immunotoxicity and the Utility of #ToxCast for Immunotoxicity Screening of Chemicals Added to #Food