Major GI #bleeding in older persons using #aspirin: incidence and risk factors in the ASPREE randomised controlled trial

There is a lack of robust data on significant gastrointestinal bleeding in older people using aspirin. We calculated the incidence, risk factors and absolute risk using data from a large randomised, controlled trial. Design Data were extracted from an aspirin versus placebo primary prevention trial conducted throughout 2010–2017 (‘ASPirin in Reducing Events in the Elderly …

Continue reading Major GI #bleeding in older persons using #aspirin: incidence and risk factors in the ASPREE randomised controlled trial

#Statin use is associated with lower prevalence of advanced liver #fibrosis in patients with type 2 diabetes

Patients with type 2 diabetes (T2D) are at increased risk of both cardiovascular disease (CVD) and advanced liver fibrosis related to non-alcoholic fatty liver disease (NAFLD). Statin use is known to reduce the incidence of CVD while evidence on an effect on NAFLD severity is limited. Methods This is a cross-sectional study performed with data …

Continue reading #Statin use is associated with lower prevalence of advanced liver #fibrosis in patients with type 2 diabetes