#mRNA vaccine-elicited antibodies to #SARS-CoV-2 and circulating variants

Here we report on the antibody and memory B cell responses in a cohort of 20 volunteers who received either the Moderna (mRNA-1273) or Pfizer-BioNTech (BNT162b2) vaccines1–4. Eight weeks after the second vaccine injection volunteers showed high levels of IgM, and IgG anti-SARS-CoV-2 spike protein (S) and receptor binding domain (RBD) binding titers. Moreover, the plasma neutralizing activity, and the relative numbers of RBD-specific memory … Continue reading #mRNA vaccine-elicited antibodies to #SARS-CoV-2 and circulating variants

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Effect of High-Intensity Strength #Training on #Knee Pain and Knee Joint Compressive Forces Among Adults With Knee #Osteoarthritis

Thigh muscle weakness is associated with knee discomfort and osteoarthritis disease progression. Little is known about the efficacy of high-intensity strength training in patients with knee osteoarthritis or whether it may worsen knee symptoms. Objective To determine whether high-intensity strength training reduces knee pain and knee joint compressive forces more than low-intensity strength training and more than attention control in patients with knee osteoarthritis. Design, … Continue reading Effect of High-Intensity Strength #Training on #Knee Pain and Knee Joint Compressive Forces Among Adults With Knee #Osteoarthritis

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