Longitudinal Associations of Midlife Accelerometer Determined #Sedentary Behavior and Physical Activity With #Cognitive Function: The CARDIA Study

To determine if accelerometer measured sedentary behavior (SED), light‐intensity physical activity (LPA), and moderate‐to‐vigorous–intensity physical activity (MVPA) in midlife is prospectively associated with cognitive function. Participants were 1970 adults enrolled in the CARDIA (Coronary Artery Risk Development in Young Adults) study who wore an accelerometer in 2005 to 2006 (ages 38–50 years) and had cognitive function assessments completed 5 and/or 10 years later. SED, LPA, … Continue reading Longitudinal Associations of Midlife Accelerometer Determined #Sedentary Behavior and Physical Activity With #Cognitive Function: The CARDIA Study

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A Randomized Controlled Trial of Repeated #Ketamine Administration for Chronic Posttraumatic Stress Disorder

Posttraumatic stress disorder (PTSD) is a chronic and disabling disorder, for which available pharmacotherapies have limited efficacy. The authors’ previous proof-of-concept randomized controlled trial of single-dose intravenous ketamine infusion in individuals with PTSD showed significant and rapid PTSD symptom reduction 24 hours postinfusion. The present study is the first randomized controlled trial to test the efficacy and safety of repeated intravenous ketamine infusions for the … Continue reading A Randomized Controlled Trial of Repeated #Ketamine Administration for Chronic Posttraumatic Stress Disorder

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