Childhood Daily #Energy Expenditure Does Not Decrease with Market Integration and Is Not Related to #Adiposity in Amazonia

Childhood overweight and obesity (OW/OB) is increasingly centered in low- and middle-income countries (LMICs) as rural populations experience market integration and lifeway change. Most explanatory studies have relied on imprecise estimates of children’s energy expenditure, restricting understanding of the relative effects of changes in diet and energy expenditure on the development of OW/OB in transitioning contexts.. ..Cross-sectional data were collected from β€œrural” (n = 43) … Continue reading Childhood Daily #Energy Expenditure Does Not Decrease with Market Integration and Is Not Related to #Adiposity in Amazonia

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Effect of #denosumab on osteolytic lesion activity after total #hip arthroplasty: a single-centre, randomised, double-blind, placebo-controlled, proof of concept trial

Osteolysis causes recurrent pain and disability after total hip arthroplasty. We investigated the effect of the human monoclonal antibody denosumab on osteolytic lesion activity in patients undergoing revision total hip arthroplasty surgery to show the biological proof of concept for a non-surgical treatment for the disease.. Findings Between Dec 12, 2012, and June 24, 2018, 51 patients were assessed for eligibility, of whom 24 were … Continue reading Effect of #denosumab on osteolytic lesion activity after total #hip arthroplasty: a single-centre, randomised, double-blind, placebo-controlled, proof of concept trial

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