Impaired intestinal epithelial barrier is highly affected in inflammatory bowel disease. Transmembrane collagens connecting the epithelial cells to the extracellular matrix have an important role in epithelial cell homeostasis. Thus, we sought to determine whether the transmembrane type 23 collagen could serve as a surrogate marker for disease activity in patients with Crohn’s disease and … Continue reading Elevated ectodomain of type 23 #collagen is a novel biomarker of the intestinal epithelium to monitor disease activity in #ulcerative colitis and #Crohn’s disease
Day: Dec 30, 2020
Using longitudinal data from a representative UK panel, we focus on a group of apparently healthy individuals with no history of disability or major chronic health condition at baseline. A latent variable structural equation model is used to analyse the predictive role of latent baseline biological health, indicated by a rich set of biomarkers, and … Continue reading #Biomarkers, disability and health care demand
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