The #Coronavirus Is Mutating. What Does That Mean for Us?

By Apoorva Mandavilli – NYT Just as vaccines begin to offer hope for a path out of the pandemic, officials in Britain this past weekend sounded an urgent alarm about what they called a highly contagious new variant of the coronavirus circulating in England. Citing the rapid spread of the virus through London and surrounding areas, Prime Minister Boris Johnson imposed the country’s most stringent … Continue reading The #Coronavirus Is Mutating. What Does That Mean for Us?

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The influence of #proton pump inhibitor therapy on the outcome of #infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies

In treating patients with inflammatory bowel disease (IBD), how concomitant medications influence the response to infliximab is largely unexplored. We aim to evaluate whether proton pump inhibitors (PPIs) affect the response to infliximab therapy in patients with IBD.. Among the five randomised controlled studies, there were 889 and 147 patients on infliximab with and without PPI therapy, respectively. Patients on PPI were older, more likely … Continue reading The influence of #proton pump inhibitor therapy on the outcome of #infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies

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