Dynamic changes in DICER levels in #adipose tissue control metabolic adaptations to #exercise

DICER is a key enzyme in microRNA (miRNA) biogenesis. Here we show that aerobic exercise training up-regulates DICER in adipose tissue of mice and humans. This can be mimicked by infusion of serum from exercised mice into sedentary mice and depends on AMPK-mediated signaling in both muscle and adipocytes. Adipocyte DICER is required for whole-body metabolic adaptations to aerobic exercise training, in part, by allowing … Continue reading Dynamic changes in DICER levels in #adipose tissue control metabolic adaptations to #exercise

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Elevated #Coronary Artery Calcium scores are associated with #tooth loss

This study explores the association between Coronary Artery Calcium (CAC) scores and dental pathology such as missing teeth, the (peri-apical) health status and restoration grade of the teeth, and the grade of alveolar bone loss seen on a dental panoramic radiograph (Orthopantomographโ€“OPG).. ..212 patients were included. We found a statistically significant association between the number of missing teeth and the CAC score. When modeling age, … Continue reading Elevated #Coronary Artery Calcium scores are associated with #tooth loss

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