Depression and anxiety are common mental disorders that increase physical health risks and are leading causes of global disability. Several forms of physical fitness could be modifiable risk factors for common mental disorders in the population. We examined associations between individual and combined markers of cardiorespiratory fitness and grip strength with the incidence of common … Continue reading Individual and combined associations between cardiorespiratory #fitness and grip strength with common #mental disorders: a prospective cohort study in the UK Biobank
Day: Nov 22, 2020
Using AI we identified baricitinib as possessing anti-viral and anti-cytokine efficacy. We now show a 71% (95% CI 0.15-0.58) mortality benefit in 83 patients with moderate-severe SARS-CoV-2 pneumonia with few drug-induced adverse events, including a large elderly cohort (median age 81 years). A further 48 cases with mild-moderate pneumonia recovered uneventfully. Using organotypic 3D cultures … Continue reading JAK inhibition reduces #SARS-CoV-2 #liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
