#Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons

Interleukin (IL)-17a has been highly conserved during evolution of the vertebrate immune system and widely studied in contexts of infection and autoimmunity. Studies suggest that IL-17a promotes behavioral changes in experimental models of autism and aggregation behavior in worms. Here, through a cellular and molecular characterization of meningeal γδ17 T cells, we defined the nearest …

Continue reading #Meningeal γδ T cells regulate #anxiety-like behavior via IL-17a signaling in neurons

#Sleep duration and affective reactivity to #stressors and positive events in daily life

Objective: Experimental evidence suggests that inadequate sleep disrupts next-day affective processing and evokes greater stress reactivity. However, less research has focused on whether sleep predicts next-day affective reactivity to naturally occurring stressors and positive events in daily life, as well as the reversed direction of association (i.e., affective reactivity to daily events as predictors of …

Continue reading #Sleep duration and affective reactivity to #stressors and positive events in daily life