Hepatic decompensation in #cirrhotic patients receiving antiviral therapy for chronic #hepatitis B

It is unclear if anti-hepatitis B virus (HBV) treatment can eliminate incident hepatic decompensation. Here we report the incidence and predictors of hepatic decompensation among cirrhotic patients receiving antiviral therapy for chronic hepatitis B.. ..818 patients (mean age, 54.9 years; 519 male [63.4%]) were included in the final analysis. During a mean follow-up of 58.1 months, 32 (3.9%) patients developed hepatic decompensation, among whom 34% … Continue reading Hepatic decompensation in #cirrhotic patients receiving antiviral therapy for chronic #hepatitis B

The Association of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in #Knee #Osteoarthritis

To examine the cross‐sectional association of ascending pain mechanisms (APM), implicated in pain sensitization (PS), and descending pain modulation with pain patterns and unpredictability of pain The Multicenter Osteoarthritis (OA) Study is a longitudinal cohort of older adults with or at risk of knee OA. Peripheral and central APM were assessed using quantitative sensory tests (QST); pressure pain thresholds (PPTs) using a handheld pressure algometer … Continue reading The Association of Pain Sensitization and Conditioned Pain Modulation to Pain Patterns in #Knee #Osteoarthritis