Risk of #amputation with #canagliflozin across categories of age and cardiovascular risk in three US nationwide databases: cohort study

..Results Across the three databases, 310 840 propensity score matched adults who started canagliflozin or a GLP-1 agonist were identified. The hazard ratio and rate difference per 1000 person years for amputation in adults receiving canagliflozin compared with a GLP-1 agonist for each group was: group 1, hazard ratio 1.09 (95% confidence interval 0.83 to 1.43), rate difference 0.12 (−0.31 to 0.55); group 2, hazard ratio … Continue reading Risk of #amputation with #canagliflozin across categories of age and cardiovascular risk in three US nationwide databases: cohort study