Selective and cross-reactive #SARS-CoV-2 #T cell epitopes in unexposed humans

Many unknowns exist about human immune responses to the SARS-CoV-2 virus. SARS-CoV-2 reactive CD4+ T cells have been reported in unexposed individuals, suggesting pre-existing cross-reactive T cell memory in 20-50% of people. However, the source of those T cells has been speculative. Using human blood samples derived before the SARS-CoV-2 virus was discovered in 2019, we mapped 142 T cell epitopes across the SARS-CoV-2 genome … Continue reading Selective and cross-reactive #SARS-CoV-2 #T cell epitopes in unexposed humans