Nine-year prospective efficacy and safety of brain-responsive #neurostimulation for focal #epilepsy

Prospectively evaluate safety and efficacy of brain-responsive neurostimulation in adults with medically intractable focal onset seizures (FOS) over 9 years.. Adults treated with brain-responsive neurostimulation within 2 year feasibility or randomized controlled trials enrolled into a long-term prospective open label trial (LTT) to assess safety, efficacy, and quality of life (QOL) over an additional 7 years. Safety was assessed as adverse events (AEs), efficacy as … Continue reading Nine-year prospective efficacy and safety of brain-responsive #neurostimulation for focal #epilepsy

Association of triage #hypothermia with in-hospital mortality among patients in the emergency department with suspected #sepsis

To identify if triage hypothermia (<36.0 °C) among emergency department (ED) encounters with sepsis are independently associated with mortality.. ..Of 1.2 billion ED encounters (95% confidence interval [CI] 1.0–1.3 billion), 3.1 million (95% CI 2.7–3.5 million) met the explicit sepsis definition; 7.4% (95% CI 75.2–9.7%) had triage hypothermia. The adjusted odds ratio (aOR) for hypothermia for in-hospital mortality was 6.82 (95% CI 3.08–15.22). The severe … Continue reading Association of triage #hypothermia with in-hospital mortality among patients in the emergency department with suspected #sepsis