Day: Jul 22, 2020

Gastroenterology, Infectivology

#Probiotic Properties of #Escherichia coli Nissle in Human Intestinal Organoids

Probiotic, or beneficial, bacteria, such as E. coli Nissle, hold promise for the treatment of human disease. More study is needed to fully realize the potential of probiotics. Safety and efficacy studies are critically important; however, mice are poor models for many human intestinal diseases. We used stem cell-derived human intestinal organoid tissues to evaluate the safety of Nissle and its ability to protect from … Continue reading #Probiotic Properties of #Escherichia coli Nissle in Human Intestinal Organoids

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Infectivology

Rapid Gel Card Agglutination Assays for Serological Analysis Following #SARS-CoV-2 Infection in Humans

High-throughput and rapid serology assays to detect the antibody response specific to severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) in human blood samples are urgently required to improve our understanding of the effects of COVID-19 across the world. Short-term applications include rapid case identification and contact tracing to limit viral spread, while population screening to determine the extent of viral infection across communities is a longer-term need. … Continue reading Rapid Gel Card Agglutination Assays for Serological Analysis Following #SARS-CoV-2 Infection in Humans

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