Complement-Dependent Synaptic Uptake and Cognitive Decline after #Stroke and Reperfusion Therapy

..This study addresses two major challenges facing the treatment of stroke in the era of reperfusion therapy: hemorrhagic transformation and the disconnect between successful revascularization and functional outcomes. We studied how complement-dependent neuroinflammation drives the pathophysiology behind these challenges using a translationally relevant strategy. Complement inhibition was achieved using B4Crry, an injury site-targeted inhibitor of … Continue reading Complement-Dependent Synaptic Uptake and Cognitive Decline after #Stroke and Reperfusion Therapy